In this post, we present the current focus of the COVID-19 literature, based on publications registered in PubMed as published during January 2021. During this month, there were 9861 publications, and 1239 keywords occurred in five or more manuscripts. We used two resolutions this month, both 1, and 1.5. The keywords divided into 6 and 12 clusters respectively. To create the map, we used the LinLog method.

In the table below, we have listed the 15 most central keywords in each cluster in the higher resolution map.

The topic in each cluster seems to be:

Cluster 1: Health care delivery
Cluster 2: Virus genetics
Cluster 3: Mental health issues
Cluster 4: Health care delivery
Cluster 5: Public health
Cluster 6: Testing
Cluster 7: Risk factors and mortality
Cluster 8: Vaccines and ethics
Cluster 9: Education and communicatioin
Cluster 10: Treatment
Cluster 11: Demographic
Cluster 12: Pregnancy

Keyword Co-occurrence map: resolution 1.0

Keyword Co-occurrence map: resolution 1.5

 

To open the map directly in VOSviewer, please use the Keyword co-occurrence MAP and NET files from January 6th, available through the Open Science Foundation (OSF) repository: https://osf.io/54gqw/

Keyword Weighted Degree Occurrences
Cluster 1: Health care delivery
retrospective studies 1219 165
hospitalization 983 118
severity of illness index 820 106
treatment outcome 605 70
time factors 487 55
prognosis 474 88
prospective studies 418 56
intensive care units 412 73
cohort studies 394 60
lung 360 62
respiration, artificial 357 38
critical care 338 67
pneumonia 304 81
biomarkers 281 53
Cluster 2: Virus genetics
animals 652 98
antibodies, viral 608 70
spike glycoprotein, coronavirus 583 75
angiotensin-converting enzyme 2 455 64
sars 360 95
antibodies, neutralizing 312 31
inflammation 300 95
cytokines 247 64
mice 237 27
ace2 235 87
cross infection 224 30
antibodies, monoclonal 219 28
protein binding 200 23
immunoglobulin g 198 21
genome, viral 183 29
Cluster 3: Mental health issues
cross-sectional studies 1173 156
surveys and questionnaires 996 137
mental health 783 190
anxiety 764 183
depression 635 150
stress, psychological 348 41
health knowledge, attitudes, practice 291 47
exercise 255 44
lockdown 244 104
students 229 33
longitudinal studies 216 27
social isolation 215 42
logistic models 205 20
stress 196 60
quality of life 195 52
Cluster 4: Health care delivery
health personnel 609 96
telemedicine 599 245
united kingdom 393 63
personal protective equipment 370 93
infection control 346 75
health services accessibility 286 45
neoplasms 286 47
delivery of health care 264 51
hospitals 193 34
primary healthcare 189 32
qualitative research 177 41
attitude of health personnel 167 23
canada 155 32
cancer 147 47
nurses 139 45
Cluster 5: Public health
public health 842 193
china 740 127
quarantine 740 124
communicable disease control 554 100
epidemiology 521 132
disease outbreaks 494 72
physical distancing 408 67
infectious diseases 340 86
health policy 337 70
global health 286 69
brazil 266 52
contact tracing 232 42
models, theoretical 195 33
epidemic 190 60
masks 188 46
Cluster 6: Testing
covid-19 testing 711 119
prevalence 491 69
covid-19 nucleic acid testing 369 42
rna, viral 365 53
respiratory infections 323 44
viruses 319 57
viral load 235 40
covid-19 serological testing 227 25
disease transmission, infectious 220 28
sensitivity and specificity 220 30
reverse transcriptase polymerase chain reaction 214 31
zoonosis 210 31
seroepidemiologic studies 205 23
antibody 186 53
nasopharynx 169 21
Cluster 7: Risk factors and mortality
risk factor 1239 197
comorbidity 748 99
mortality 675 187
diabetes mellitus 397 52
age factors 344 39
risk assessment 289 45
cardiovascular diseases 247 53
hypertension 242 37
sex factors 240 25
obesity 239 53
republic of korea 138 20
diabetes 116 37
angiotensin-converting enzyme inhibitors 115 18
smoking 115 18
body mass index 113 12
Cluster 8: Vaccines and ethics
united states 686 131
covid-19 vaccines 385 81
socioeconomic factors 313 52
vaccine 294 110
vaccination 288 77
healthcare disparities 157 28
health status disparities 156 27
ethnic groups 146 21
vulnerable populations 143 27
influenza, human 119 21
clinical trials 93 37
immunization programs 87 13
minority groups 87 10
treatment 87 40
social determinants of health 86 20
Cluster 9: Education and communicatioin
communication 265 47
social media 196 50
education, distance 176 34
students, medical 153 26
curriculum 119 27
education, medical 102 19
medical education 97 33
leadership 88 19
clinical competence 81 14
nigeria 77 19
california 76 13
education 76 28
education, medical, undergraduate 65 10
misinformation 61 12
consumer health information 58 8
Cluster 10: Treatment
antiviral agents 791 108
hydroxychloroquine 387 62
anti-bacterial agents 328 32
drug repositioning 280 39
clinical trials as topic 271 36
azithromycin 218 29
antimalarials 181 21
drug combinations 168 16
safety 141 31
adenosine monophosphate 131 14
alanine 131 14
uncertainty 124 24
drug synergism 119 10
enzyme inhibitors 110 8
efficacy 93 13
Cluster 11: Demographic
adolescent 1672 200
aged, 80 and over 1475 173
children 1288 206
italy 816 105
child, preschool 691 72
infant 644 77
incidence 450 68
spain 317 42
germany 200 32
risk 199 33
registry 176 27
sex distribution 165 14
age distribution 163 14
databases, factual 157 17
nursing homes 145 32
Cluster 12: Pregnancy
pregnancy 410 95
coronavirus infection 237 61
pregnancy complications, infectious 162 23
anosmia 96 32
infectious disease transmission, vertical 62 8
smell 55 17
delivery, obstetric 52 5
dysgeusia 50 9
data collection 45 7
domestic violence 42 9
pregnancy outcome 38 6
hyposmia 37 13
maternal mortality 34 6
prenatal care 31 6
breastfeeding 29 13