In this week’s update, we are presenting something slightly different; the current focus of the COVID-19 literature, based on publications registered in PubMed as published in the past 3 weeks (21 days). This resulted in 6001 publications. There were 677 keywords that occurred in five or more manuscripts. These divided into five main clusters. To create the map, we used the LinLog method. The minimum cluster size was set to 15.

  • Cluster 1 (red) covers literature focusing on Public health strategies, treatment, and the global impact of COVID-19.
  • Cluster 2 (green) includes literature on the role of existing drugs and vaccines in the current pandemic.
  • Cluster 3 (blue) focuses on demographics and risk factors.
  • Cluster 4 (yellow) covers literature concentrated on understanding the nature of the virus.
  • Cluster 5 (Purple) addresses the association between COVID-19 and mental health.

We find it interesting that there does not seem to be a big shift in publication focus from earlier in the pandemic; however, expect this to change as more time has elapsed, allowing for other types of studies to mature and be ready for publication, especially on topics relating to social consequences of the pandemic.

Table of the most central keywords in each cluster

(Centrality measure used is weighted degree centrality/total link strength)

Cluster 1 Cluster 2 Cluster 3 Cluster 4 Cluster 5
pandemic sars female clinical laboratory techniques surveys and questionnaires
coronavirus infection antiviral agents male rna, viral anxiety
viral pneumonia animals middle aged real time polymerase chain reaction prevalence
betacoronavirus antibodies, viral adult viruses mental health
italy hydroxychloroquine aged pneumonia cross-sectional studies
united states cytokines china sensitivity and specificity depression
telemedicine inflammation risk factor reverse transcriptase polymerase chain reaction stress, psychological
quarantine peptidyl-dipeptidase a young adult epidemiology cancer
public health viral vaccines retrospective studies zoonosis health knowledge, attitudes, practice
personal protective equipment spike glycoprotein, coronavirus aged, 80 and over nasopharynx fear
disease outbreaks cytokine release syndrome adolescent infection social media
infection control thrombosis children immunoglobulin g family
pregnancy cardiovascular diseases treatment outcome respiratory infections olfaction disorders
health personnel vaccine severity of illness index outbreak students
spain renin-angiotensin system lung transmission adaptation, psychological
cities influenza, human hospitalization serological test communication
incidence mice time factors patient selection stress
air pollution angiotensin-converting enzyme inhibitors prognosis viral load emotions
practice guidelines as topic chloroquine tomography, x-ray computed immunoglobulin m smell
global health immunologic factors risk assessment diagnosis, differential ageusia

To open the map directly in VOSviewer, please use the latest MAP and NET files, available through the Open Science Foundation (OSF) repository: